Journal of Organic Chemistry p. 2498 - 2502 (1985)
Update date:2022-09-26
Topics:
Russell, Glen A.
Dedolph, D. F.
1-Chloro-1-cyclopropyl-1-nitroethane and 2-chloro-2-nitrohept-6-ene underwent free radical chain substitution reactions in which the chlorine was replaced by the nucleophiles Me2C=NO2-, c-C3H5C(CH3)=NO2-, CH2=CH(CH2)3C(CH3)=NO2-, (EtO2C)2CMe-, Me3C(O-=CH2 or the enolate anion of 2-methyl-1,3-cyclopentanedione.Ring opening or closure reactions were not observed in these substitutions or in the reaction of 1-chloro-1-cyclopropyl-1-nitroethane with (n-Bu)3SnH to form 1-cyclopropyl-1-nitroethane.A 1-nitro substituent retards the rate of the cyclopropylcarbinyl radical ring opening by a factor of the at least 104 at 40 deg C.
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