An Efficient Copper-Catalyzed Amination of Aryl Halides
COMMUNICATIONS
[a]
Table 3. Copper-catalyzed amination of aryl bromides.
Acknowledgements
We thank the 100-talent program of CAS, National Natural
Science Foundation (Grant # 20802077, 90813033) and Na-
tional High Technology Research and Development Program
(
863 program, Grant # 2007AA02Z490) for financial sup-
port.
[b]
Entry
1
ArÀBr
ArÀNH2
Yield [%]
[
c]
79, 95
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[
a]
Reaction conditions: Ar-Br (1.0 mmol), commercial 28%
aqueous NH3 (5.0 equiv., 0.3 mL), CuBr 10 mol%, L3
2
0 mol%, K PO (2.5 mmol), DMSO (2.0 mL) stirred at
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3
4
1
108C for 24 h under argon.
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[
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ꢁ 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
1725