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Benzylic Carbon Oxidation
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(9) Oxone® is a 2:1:1 mixture of KHSO5, KHSO4, and K2SO4.
For the use of Oxone® for the oxidation of 2IBAcid to IBX,
see: Frigerio, M.; Santagostino, M.; Sputore, S. J. Org.
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References and Notes
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(11) We arrived at this compensation by estimating the amount of
Oxone® remaining after heating a solution of Oxone® in the
solvent mixture employed for the reaction for 48 h. We used
the Dupont® reported iodometric procedure for the
estimation of Oxone® available at: http://www.dupont.com/
oxone/techinfo/index.html (accessed May 2008).
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(4) Caution! IBX is known to explode upon impact or heating at
>200 °C, see: Plumb, J. B.; Harper, D. J. Chem. Eng. News
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Synlett 2009, No. 1, 117–121 © Thieme Stuttgart · New York