2
60 JOURNAL OF CHEMICAL RESEARCH 2012
A typical procedure for the oxidative bromination of toluene or a
Received 2 December 2011; accepted 24 February 2012
Paper 1101023 doi: 10.3184/174751912X13333614619977
Published online: 10 May 2012
substituted toluene by HBr/H O in the micro reactor under incandes-
2
2
cent light conditions at room temperature is as follows (see Fig. 1).
The hydrogen peroxide solution, the hydrogen bromide solution and
the (substituted) toluene were each pumped through one of three
single-channel micro-injection pumps. The hydrogen peroxide and
hydrogen bromide solutions were premixed before entering the two-
channel reactor. The molar ratio of reactants and the reaction (resi-
dence) time were controlled by varying the flow rates of the pumps.
The product mixture was filtered and the filtrate was washed with
aqueous NaHSO to remove the unreacted Br and H O and dried
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This project was supported by the National Natural Science
Foundation of Zhejiang Province (Y407306) and the National
Natural Science Foundation of China (20876148).
2
S. Adimurthy, S. Ghosh, P.U. Patoliya, G. Ramachandraiah, M. Agrawal,
M.R. Ghandi, S.C. Upadhyay, P.K. Ghosh and B.C. Ranu, Green Chem.,
2008, 10, 232.