10.1002/ejoc.202001593
European Journal of Organic Chemistry
COMMUNICATION
A plausible mechanism of the reaction is presented. This
method shows, apart from the ease to prepare scaffolds w ith
medicinal interest, also the potential of an organocatalyst to
perform photochemical reactions in very good yields without
the need for special conditions, such as dry solvents and inert
atmosphere or metal catalysts.
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ExperimentalSection
In a glass vial, benzaldehyde (4d) (5 mg, 0.05 mmol), maleimide (0.25
mmol) and N,N-dimethylaniline (0.50 mmol) were dissolved in N,N-
dimethylacetamide (1.5 mL). The vial was left stirring under household
bulb irradiation (2 x 85W household lamps) for 16 h. The desired
product was isolated after purification by column chromatography .
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Acknowledgements
The authors gratefully acknow ledge the Hellenic Foundation
for Research and Innovation (HFRI) for financial support
through a grant, which is financed by 1st Call for H.F.R.I.
Research Projects to Support Faculty Members & Researchers
and the procurement of high-cost research equipment grant
(grant number 655). N. F. N. would like to thank the State
Scholarships Foundation (IKY) for financial support through a
doctoral fellowship, which is co-financed by Greece and the
European Union (European Social Fund-ESF) through the
Operational Programme «Human Resources Development,
Education and Lifelong Learning» in the context of the project
“Strengthening Human Resources Research Potential via
Doctorate Research” (MIS-5000432), implemented by the
State Scholarships Foundation (ΙΚΥ)». The authors would like
to thank Prof. V. Constantinou (Agricultural University of
Athens) for access to the fluorescence spectrometer. Also,
COST Action C-H Activation in Organic Synthesis (CHAOS)
CA15106 is acknow ledged forhelpfuldiscussions.
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Keywords: Benzaldehyde Photochemistry
Pyrrolo[3,4-
c]quinolinoles N-substituted maleimides
N,N-disubstituted
aniline
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