Journal of the American Chemical Society p. 5667 - 5670 (1994)
Update date:2022-08-11
Topics:
Martens
Klein Gebbink
Feiters
Nolte
A novel metallohost containing a substrate-binding site and two copper ions held by two bis-pyrazole ligand sets is described. The cavity of this molecule can bind dihydroxybenzene guests (association constants in chloroform are in the range Ka = 2000-3000 M-1). In the presence of benzylic alcohols the Cu(II) centers of the metallohost are reduced to Cu(I). During this process the alcohols are oxidized to aldehydes. Benzylic alcohols possessing phenolic hydroxyl functions are extremely effective in the reduction reaction. It is believed that they are bound in the cavity of the metallohost and are oriented in the correct position with respect to the copper centers. This results in a rate enhancement of at least 4 orders of magnitude for the oxidation reaction.
View MoreJinan Kaypharm Chemical Co.,Ltd
Contact:86-0531-86986780
Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
Jiangxi Hessence Chemicals Co., Ltd.
Contact:+86 796 3511924
Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Xi'an Unique Electronic and Chemical Co., Ltd.
Contact:+86-029-88238008
Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Jiangsu Willing Bio-Tech Co ltd
website:http://www.willingbio.com/
Contact:+86 18796909136
Address:No 18 Guoqiao Road
Huaihua Baohua Biotechnology Co.,Ltd
website:http://www.baochengchem.com
Contact:86-519-82698291
Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
Doi:10.1021/ja00011a018
(1991)Doi:10.1021/acs.orglett.1c00077
(2021)Doi:10.1134/S1070328417100050
(2017)Doi:10.1016/j.molstruc.2008.05.037
(2008)Doi:10.1016/S0040-4039(00)71261-5
(1991)Doi:10.1021/jo00145a018
(1982)