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Table 3
References and notes
Scale up of nitrilie 1na
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O
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3n
1
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3
15
16
7
84
93
0
0
80
91
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a
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s
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b
Conversion by GCMS.
c
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able alternative to batch procedures, especially when scaling up.
All the examples reported are obtained in good to excellent yields
and selectivities using a simple and economical set up. They were
selected as representatives for aryl, benzyl, alkyl and heterocyclic
aldehydes, providing good starting points for the future analogues
to be reduced.
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Acknowledgments
The authors want to thank the financial support by the DGCYT
of Spain (project CTQ2010-14975/BQU) and the Junta de Comunid-
ades de Castilla- La Mancha (Program HITO 2010-54 and project
PII2I09-0100), and Dr. Daniel Oelhrich for his assistance during
the preparation of the current article.