10.1002/anie.202105857
Angewandte Chemie International Edition
RESEARCH ARTICLE
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transformation, the seven-membered spiropyrazolones were
constructed for the first time and diazopyrazolones acted as
unexpected 1C synthons. In addition, these reactions also have a
broad range of substrates, along with moderate to good yields.
The multiple reaction modes and valuable transformations will
offer structural and biological potentials for further drug discovery.
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We are grateful to the National Natural Science Foundation of
China (21977106, 21632008 and 81620108027), Shanghai
Science and Technology Development Funds (19431901000 and
19431901200), Science and Technology Commission of
Shanghai Municipality (18JC1411304), Youth Innovation
Promotion Association CAS for financial support.
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Keywords: N-N bond activation • C(sp3)-H bond activation •
[n+1] cyclization • spiropyrazolones • pyrazolidinones
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