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Fig. 3. Plots of kfcnat=kcf0at ratio against
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data were obtained at physiological pH and in the absence of bo-
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dependence with regard to Hammett’s equation is the same for
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ditions support the mechanism proposed in Scheme 1SM (Supple-
mentary material).
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Acknowledgments
dicopper (II) complex supported by dinucleating ligand, J. Am. Chem. Soc. 128
(2006) 3874–3875.
This paper was partially supported by grants from: Ministerio
de Educación y Ciencia (Madrid, Spain), Project BIO2009-12956;
Fundación Séneca (CARM, Murcia, Spain), Projects 08856/PI/08
and 08595/PI/08, and Consejería de Educación (CARM, Murcia,
Spain), BIO-BMC 06/01-0004. JLMM hold fellowships from
Fundación Caja Murcia (Murcia, Spain). J.B. thanks the MICINN
for a Ramón y Cajal Fellowship, cofinanced by the European Social
Fund.
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Stack, Tyrosinase reactivity in a model complex: an alternative hydroxylation
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Appendix A. Supplementary data
Supplementary data associated with this article can be found, in
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