Synthetic Communications p. 1242 - 1248 (2016)
Update date:2022-08-28
Topics:
Alapati, Mohan Lakshmi Punna Rao
Abburu, Sridhar Rao
Mutyala, Krishnaji Rao
Mukkamala, Saratchandra Babu
An efficient one-pot synthesis of N-arylbenzamide is described via reaction of phenylboronic acid/aryl bromide with benzamide in the presence of CuI (5?mol%) as catalyst, 4-dimethylaminopyridine (20?mol%) as the ligand, and Cs2CO3(2?mmol) as the base. This protocol was applied to synthesize a small library of N-arylbenzamide in high yields.
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Doi:10.1246/bcsj.49.3367
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