Journal of Organic Chemistry p. 129 - 134 (1987)
Update date:2022-08-29
Topics:
Soucy
Favreau
Kayser
A problem of 3-methoxyphthalide reduction by metal hydrides was reinvestigated. Various effects controlling selectivity of reductions in 3-substituted phthalides were studied, and a qualitative interpretation of the results is now proposed. Methods for obtaining enhanced yields of one or the other lactonic product were developed.
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