Tetrahedron p. 319 - 323 (1981)
Update date:2022-08-23
Topics:
Lion, Claude
Dubois, Jacques-Emile
t-Alkylation of carboxylic esters via their ketene alkyl trimethylsilyl acetels by the Friedel-Crafts reaction allows the synthesis of new higly hindered compounds.A new route using sodium amide in dimethoxyethane, for the preparation of trimethylsilyl enol ethers of ketones, is described.The α-butylation of these compounds permits the synthesis of new crowded pentasubstituted ketones.The limits as well as the performance of the method have been studied.
View MoreContact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Contact:18698110882
Address:1303 No2 building,LuoMa Garden,YongAn Road,Hexi District,Tianjin city
shanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Shanghai PuYi Chem-Tech Co.,Ltd.
Contact:+86-21-57687505-227
Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.
website:http://www.zenvasino.com
Contact:+86-138-72658998
Address:Shibeishan Road,Zhijiang, Hubei, China
Doi:10.1080/00397910008086904
(2000)Doi:10.1016/j.dyepig.2020.108853
(2021)Doi:10.1021/ja01641a039
(1954)Doi:10.1039/c9tc03941d
(2019)Doi:10.1021/acs.orglett.6b03326
(2016)Doi:10.1248/cpb.38.2281
(1990)