RSC Advances p. 11023 - 11031 (2016)
Update date:2022-08-16
Topics:
Sazegar, Mohammad Reza
Mahmoudian, Shaya
Mahmoudi, Ali
Triwahyono, Sugeng
Jalil, Aishah Abdul
Mukti, Rino R.
Nazirah Kamarudin, Nur H.
Ghoreishi, Monir K.
The mesoporous silica structure (MSN) was synthesized using the sol-gel method followed by aluminum grafting and protonation and was then denoted as HAlMSN (Si/Al = 18.9). N2 physisorption confirmed the mesoporous structure with a pore diameter of 3.38 nm. 27Al NMR showed the presence of framework and extra-framework aluminum structures, which led to the formation of strong Lewis and Br?nsted acidic sites. HAlMSN catalyzed the synthesis of (E)-chalcones through the Claisen-Schmidt reaction. Chalcone derivatives have been applied as biologically active compounds with anti-cancer, anti-inflammatory and diuretic pharmacological activities. The products were obtained via reactions on the protonic acid sites of HAlMSN. The significant advantages of this reaction are high yield, easy work up, short reaction time and also compatibility with various organic solvents. The products were obtained in an excellent conversion of 97% at 298 K. The results show that the electron donating substituents exhibit higher conversion in comparison to electron withdrawing substituents. The stability of the catalyst was investigated by reusing it five times for (E)-chalcone production and there was only a slight decrease in its catalytic activity. The highest product of (E)-chalcone was observed with a 1:2 molar ratio of benzaldehyde/acetophenone. A comparative study in chalcone synthesis using the heterogeneous catalysts demonstrated that HAlMSN has a significantly high activity at low temperature.
View MoreContact:0571-
Address:zhejing
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Zouping Mingxing Chemical Co.,Ltd.
website:http://www.zoutong.com.cn
Contact:86-543-2240068 2240067
Address:428 Daixi Third Road Zouping County Shandong Province China
Contact:+86-511-88790000
Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016
Contact:0833-5590788/5590338/5590055
Address:Victory in the town of Red Star Village,Mount Emei City,industrial concentration area storage processing logistics parkpark
Doi:10.1134/S0023158411020054
(2011)Doi:10.1007/BF00807412
(1996)Doi:10.1002/chem.201801740
(2018)Doi:10.1016/j.ejmech.2015.11.009
(2016)Doi:10.1016/j.dyepig.2017.02.004
(2017)Doi:10.1021/acs.orglett.6b02636
(2016)