Journal of the Iranian Chemical Society
Recovering and recycling the (R)‑(+)‑α‑phenyl
ethylamine (11)
Compliance with ethical standards
Conflict of interest None.
Mother liquor of the step 2 which was explained above was
warmed to 70 °C; then, K CO (2 M) was added dropwise
2
3
to adjust the pH at 9 and the solution was then stirred for 1 h.
Then, it was cooled to 25–30 °C and extraction was accom-
plished by chloroform or ethyl acetate. The solvent was dis-
tilled oꢁ under vacuum at 50–55 °C for 2 h. (R)-(+)-α-
phenylethylamine was maintained at a yield of 88%.
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Acknowledgements We acknowledge “Deputy of Research and Tech-
nology” Tabriz University of Medical Sciences for ꢀnancial support.
We thank the oꢂcials of the pharmaceutical chemistry and pharma-
ceutical control laboratories of Pharmacy Faculty, Tabriz University
of Medical Sciences for their cooperation during the study. We also
appreciate Ms. Akram Faridi and Ms. Shirin Ahmadi for their sin-
cere help. This paper is based on the MSc thesis (7.) submitted by A.
Mansoori, Pharmacy Faculty, Tabriz University of Medical Sciences.
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