T. Razzaq, T. N. Glasnov, C. O. Kappe
SHORT COMMUNICATION
Figure 2. Conversion at different temperatures/online reaction optimization for the Newman-Kwart rearrangement of O-thiocarbamate
4a and 4b in NMP and DME as solvents (Scheme 1, Reaction 2). Flow processing (100–330 °C, 60–80 bar), 1 mLmin–1 flow rate, 4 mL
stainless steel coil, residence time 4 min.
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Acknowledgments
This work was supported by a grant from the Christian Doppler
Society (CDG). T. R. thanks the Higher Education Commission of
Pakistan for a Ph.D. scholarship. We acknowledge Thales Nano-
technology Inc. for the provision of the X-Cube Flash reactor.
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