Organic Letters
Letter
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(14) Under the optimized reaction conditions, the starting material
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dearomatization process caused by the 1,3-shift of copper to the 3
position of a thiophene ring.
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(5) For representative examples of enantioselective reduction
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reduction methods of β-amino ketones to obtain γ-amino alcohols,
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(8) For representative examples of C−H amination-based stereo-
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(9) For an example of asymmetric synthesis of γ-amino alcohols by
hydroxy-directed aziridination and aziridine hydrosilylation, see:
(a) Zhang, Y.-Q.; Bohle, F.; Bleith, R.; Schnakenburg, G.; Grimme,
(15) For representative examples for asymmetric synthesis of (S)-
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dapoxetine, see: (a) Torre, O.; Gotor-Fernandez, V.; Gotor, V.
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(10) For a minireview on the copper-catalyzed asymmetric
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D
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