Tetrahedron Letters p. 155 - 158 (1980)
Update date:2022-08-16
Topics:
Canonne, Persephone
Foscolos, George B.
Lemay, Gilles
Use of benzene containing one equivalent of ether as solvent in Grignard reactions of nitriles at room temperature, leads to increased yields of the corresponding ketones compared to results obtained for the same reactions in ether.A useful consequence of this is that undesirable side reactions are virtually eliminated.
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