Monatshefte fur Chemie p. 1187 - 1190 (2013)
Update date:2022-08-16
Topics:
Huang, Jia-Min
Qian, Chao
Feng, Lie
Chen, Yun-Bin
Chen, Xin-Zhi
The amination of aliphatic alcohols in the gas-solid phase was investigated in a fixed-bed reactor in the presence of CuO-NiO/γ-Al2O 3 as the catalyst. This catalytic system was successfully applied for both the N-methylation of aliphatic amines and N-alkylation of piperidine with primary or secondary alcohols. N-Alkylation of piperidine with low-carbon alcohols resulted in high conversions and selectivities, and the conversion of piperidine and the selectivities toward the desired products declined gradually with the increase of the carbon number of aliphatic alcohols. The influence of varied conditions on the N-cyclohexylation of piperidine was also evaluated, including liquid hourly space velocity (LHSV), temperature and the catalyst; especially the catalyst had the greatest impact. Finally, the test of the catalyst's stability was performed.
View MoreNingBO Hong Xiang Biochem.Co.Ltd
website:http://www.hxbiochem.com
Contact:0574-66003444
Address:Ning Bo Bei Lun
Taizhou YOJOY Chemical Co., Ltd.
Contact:13857143241
Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Puyang Willing Chemicals Co.,Ltd.
Contact:86-393-4840366
Address:Puyang Henan China
Contact:732.938.2777
Address:5012 Industrial Road Farmingdale, NJ 07727
Shanghai Bocimed Pharmaceutical Co., Ltd.
website:http://www.bocimed.com
Contact:+86-21-68861632
Address:Building 1, Lane 647, Songtao Road, Zhangjiang High-Tech Park, Shanghai
Doi:10.2478/s11696-013-0367-z
(2013)Doi:10.1016/S0040-4039(00)71614-5
(1967)Doi:10.1002/chem.200802678
(2009)Doi:10.1021/ml500507v
(2015)Doi:10.1016/j.tet.2006.03.114
(2006)Doi:10.1016/S0040-4039(01)81860-8
(1981)