Synthetic Communications p. 151 - 157 (1992)
Update date:2022-08-28
Topics:
Hudlicky
Natchus
Nugent
An efficient, four step synthesis of chiral enone 2a [(+)-2,3-(isopropylidenedioxy)-4-cyclopentenone] from diol 1a (X = Cl), available from microbial oxidation of chlorobenzene, is described. This synthesis is a vast improvement over that previously reported and compares very favorably with others in the literature.
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