Synlett p. 925 - 928 (1997)
Update date:2022-08-12
Topics:
Kn?lker, Hans-Joachim
Braxmeier, Tobias
A novel phosgene-free procedure for the synthesis of α-isocyanato carboxylic acid esters starting from α-amino acid esters has been achieved. The isocyanates are obtained enantiomerically pure (> 99% ee) by a DMAP-catalyzed isocyanation with di-tert-butyl
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