Molecules 2017, 22, 84
7 of 8
10. Batista, D.; Schwarz, S.; Loesche, A.; Csuk, R.; Costa, P.J.; Oliveira, M.C.; Xavier, N.M. Synthesis of
0
glucopyranos-6 -yl purine and pyrimidine isonucleosides as potential cholinesterase inhibitors. Access to
pyrimidine-linked pseudodisaccharides through Mitsunobu reaction. Pure Appl. Chem. 2016, 88, 363–379.
11. Lin, T.S.; Luo, M.Z.; Liu, M.C.; Pai, S.B.; Dutschman, G.E.; Cheng, Y.C. Synthesis and biological evaluation of
0
0
2 ,3 -dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus
(HIV) and hepatitis B virus (HBV). J. Med. Chem. 1994, 37, 798–803. [CrossRef] [PubMed]
12. Ma, T.; Pai, S.B.; Zhu, Y.L.; Lin, J.S.; Shanmuganathan, K.; Du, J.; Wang, C.; Kim, H.; Newton, M.G.; Cheng, Y.C.
Structure-activity relationships of 1-(2-deoxy-2-fluoro-β-L-arabino-furanosyl) pyrimidine nucleosides as
anti-hepatitis B virus agents. J. Med. Chem. 1996, 39, 2835–2843. [CrossRef] [PubMed]
13. Suzich, J.; Tamura, J.; Palmer-Hill, F.; Warrener, P.; Grakoui, A.; Rice, C.; Feinstone, S.; Collett, M. Hepatitis C
virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related
pestivirus and flavivirus enzymes. J. Virol. 1993, 67, 6152–6158. [PubMed]
14. Klumpp, K.; Lévêque, V.; Le Pogam, S.; Ma, H.; Jiang, W.R.; Kang, H.; Granycome, C.; Singer, M.; Laxton, C.;
Hang, J.Q. The novel nucleoside analog R1479 (40-azidocytidine) is a potent inhibitor of NS5B-dependent
RNA synthesis and hepatitis C virus replication in cell culture. J. Biol. Chem. 2006, 281, 3793–3799. [CrossRef]
15. Fyfe, J.; Keller, P.; Furman, P.; Miller, R.; Elion, G. Thymidine kinase from herpes simplex virus phosphorylates
the new antiviral compound, 9-(2-hydroxyethoxymethyl) guanine. J. Biol. Chem. 1978, 253, 8721–8727.
16. Smith, K.O.; Galloway, K.S.; Kennell, W.L.; Ogilvie, K.K.; Radatus, B.K. A new nucleoside analog,
9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl] methyl] guanine, highly active in vitro against herpes simplex
virus types 1 and 2. Antimicrob. Agents Chemother. 1982, 22, 55–61. [CrossRef] [PubMed]
17. Vince, R.; Hua, M.; Brownell, J.; Daluge, S.; Lee, F.; Shannon, W.M.; Lavelle, G.C.; Qualls, J.; Weislow, O.S.;
Kiser, R. Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against
human immunodeficiency virus in vitro. Biochem. Biophys. Res. Commun. 1988, 156, 1046–1053. [CrossRef]
18. Rabkin, C. AIDS and cancer in the era of highly active antiretroviral therapy (HAART). Eur. J. Cancer 2001
,
19. Mallal, S.A.; John, M.; Moore, C.B.; James, I.R.; McKinnon, E.J. Contribution of nucleoside analogue reverse
transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. Aids 2000, 14, 1309–1316.
20. Lai, C.L.; Shouval, D.; Lok, A.S.; Chang, T.T.; Cheinquer, H.; Goodman, Z.; DeHertogh, D.; Wilber, R.;
Zink, R.C.; Cross, A. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B.
21. Miwa, M.; Ura, M.; Nishida, M.; Sawada, N.; Ishikawa, T.; Mori, K.; Shimma, N.; Umeda, I.; Ishitsuka, H.
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively
in tumours by enzymes concentrated in human liver and cancer tissue. Eur. J. Cancer 1998, 34, 1274–1281.
22. Darrington, D.L.; Vose, J.M.; Anderson, J.R.; Bierman, P.J.; Bishop, M.R.; Chan, W.C.; Morris, M.E.;
Reed, E.C.; Sanger, W.G.; Tarantolo, S.R. Incidence and characterization of secondary myelodysplastic
syndrome and acute myelogenous leukemia following high-dose chemoradiotherapy and autologous
stem-cell transplantation for lymphoid malignancies. J. Clin. Oncol. 1994, 12, 2527–2534. [PubMed]
23. Yamaoka, N.; Aso, K.; Matsuda, K. New Syntheses of Nucleosides. 1a The Syntheses of Glycopyranosides of
Purines, Pyrimidine, and Benzimidazole. J. Org. Chem. 1965, 30, 149–152. [CrossRef]
24. Jungmann, O.; Pfleiderer, W. A new efficient method in nucleoside synthesis. Tetrahedron Lett. 1996, 37,
25. Niedballa, U.; Vorbrüggen, H. Synthesis of nucleosides 17. A general synthesis of N-glycosides. 6. On the
mechanism of the stannic chloride catalyzed silyl Hilbert-Johnson reaction. J. Org. Chem. 1976, 41, 2084–2086.
26. Vorbrüggen, H.; Krolikiewicz, K.; Bennua, B. Nucleoside syntheses, XXII1) Nucleoside synthesis with
trimethylsilyl triflate and perchlorate as catalysts. Chem. Ber. 2007, 114, 1234–1255. [CrossRef]
27. Catry, M.; Madder, A. Synthesis of Functionalised Nucleosides for Incorporation into Nucleic Acid-Based
Serine Protease Mimics. Molecules 2007, 12, 114–129. [CrossRef]