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phobic groups corresponding to the i, i+1, i+2, i+4, and
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PPIs. Work towards this end is ongoing in our laboratory
and will be reported in due course.
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Acknowledgments
The authors thank Cancer Research (CRUK) for a medicinal
chemistry studentship (to A. R. B.).
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for the C-8 methyl substituent was observed, which indicates a
completely face-selective hydrogenation.
Received: April 3, 2013
Published Online: July 25, 2013
Eur. J. Org. Chem. 2013, 5566–5569
© 2013 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
www.eurjoc.org
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