10.1002/anie.201803426
Angewandte Chemie International Edition
COMMUNICATION
Das, P. J. Dyson, Angew. Chem. Int. Ed. 2016, 55, 292-296; Angew.
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resulting material shows a distinctive nitrogen-modified titanium
structure through partial implementation of nitrogen into the TiO2
support. The optimal catalyst system displays good activity and
selectivity for pyridine hydrogenation under acid free conditions,
which is a highly demanding transformation. Several substituted
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pyridines
were
successfully
hydrogenated
into
the
corresponding functionalized piperidines in water as solvent.
The reusability of the catalyst and its application for the
synthesis of bioactive compounds were demonstrated, too.
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Acknowledgements
The Federal Ministry of Education and Research (BMBF) and
the State of Mecklenburg-Vorpommern are gratefully
acknowledged for their generous support. We thank the
analytical department of the Leibniz-Institute for Catalysis,
Rostock for their excellent analytical service.
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Keywords: Hydrogenation • Pyridine • Cobalt • Heterogeneous
catalysis • Titanium oxide
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