9
46
SPIEZIA ET AL.
thyroid nodules and compressive nontoxic nodular goiter. 15. Zingrillo M, Torlontano M, Chiariella R Ghiggi MR, Nir-
In addition, this technique appears to be safe and well tol-
erated, notwithstanding the use of multiple needles and ses-
sions. These data are very encouraging. However, this is a
preliminary study including a small series of patients with
nodule volume less than 20 mL. Therefore, future prospec-
tives and randomized clinical trials with large series of pa-
tients, larger nodule volume, and long follow-up, are needed
to confirm these data and to establish the role of LTA in the
therapeutic strategy of thyroid nodules.
chiov, Bisceglia M, Trischitta V 1999 Percutaneous ethanol
injection may be a definitive treatment for symptomatic thy-
roid cystic nodules not treatable by surgery: Five-year fol-
low-up study. Thyroid 9:763–767.
1
1
6. Livraghi T, Paracchi A, Ferrari C, Bergonzi M, Garavaglia
G, Raineri P, Vettori C 1990 Treatment of autonomous nod-
ules with percutaneous ethanol injection preliminary results.
Radiology 175:827–829.
7. Martino E, Murtas ML, Loviselli A, Piga M, Petrini L, Mic-
coli P, Pacini F 1992 Percutaneous ethanol injection for treat-
ment of autonomously functioning thyroid nodules. Surgery
Acknowledgments
1
12:1161–1164.
We thank Claudio Maurizio Pacella, of the Departments 18. Lippi F, Ferrari C, Manetti L, Rago T, Santini F, Monzani F,
Bellitti P, Papini E, Busnard B, Angelini F, Pinchera A 1996
Treatment of solitary autonomous thyroid nodules by per-
cutaneous ethanol injection: Results of an Italian multicen-
ter study. The Multicenter Study Group. J Clin Endocrinol
Metab 81:3261–3264.
of Diagnostic Imaging and Interventional Radiology, Os-
pedale Regina Apostolorum, Albano L , Rome, for teaching
the laser thermal ablation methodology.
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