Tetrahedron Letters p. 2705 - 2706 (1998)
Update date:2022-08-11
Topics:
Hansen, Marvin M.
Riggs, Jennifer R.
Boc2O and DMAP were used to protect hindered phenols as their Boc derivatives under mild conditions. Deprotection conditions were developed to suppress loss of a tert-butyl group from the aromatic ring, or alkylation of an additional tert-butyl group at an unsubstituted ortho or para position.
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