Journal of Organic Chemistry p. 2743 - 2747 (1983)
Update date:2022-08-16
Topics:
Tanner, Dennis D.
Ruo, Tomoki C.-S.
Takiguchi, Hideki
Guillaume, Andre
Reed, Darwin W.
et al.
The competitive N-bromosuccinimide (NBS) bromination of cyclopentane vs. cyclohexane was shown to proceed by a mechanism dominated by either a bromine atom chain, a succinimidyl chain, or a mixed chain.The dominance of each of the major chain-carrying processes depends upon the solvents used, to some degree upon the reactivity of the substrate, and upon the additives (molecular bromine or ethylene) used to moderate or enhance one or the other of the chain processes.No evidence was obtained, from studies of the NBS halogenation of the two substrates used, which required the intermediacy of an excited-state succinimidyl radical to explain the reactivities obtained.The observation that β-bromopropionyl isocyanate is produced under all of the reaction conditions precludes the requirement that brominations using the NBS-Br2 reagent proceed exclusively by a radical species whose reactions do not correlate with a ring-opening process.
View MoreChangzhou Hopschain Chemical Co.,Ltd
Contact:86-519-85528066
Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Quzhou Ruiyuan chemical Co., Ltd
Contact:+86-570-3039321/3039361/3039308
Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.
YingYing Pharmaceutical Co.,Ltd
Contact:86-18854126208
Address:55#, yingxiongshan road
hangzhou verychem science and technology co.ltd
website:http://www.verypharm.com
Contact:+86-571-88162785; 88162786
Address:F1502, 753 Shenhua road, Hangzhou, China
Jiangsu Zhenfang Chemical CO.,LTD.(Suzhou Zhenfang Chemical Factory)
Contact:+86-512-69598882
Address:Room1201, Jiayuan Road No.1018, Xiangcheng District, Suzhou, China
Doi:10.1016/S0040-4039(01)93768-2
(1989)Doi:10.1007/s11172-008-0205-6
(2008)Doi:10.1055/s-0036-1588668
(2017)Doi:10.1021/ie50447a613
(1947)Doi:10.1021/ol016526l
(2001)Doi:10.1039/c6ra20101f
(2016)