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(
5
2
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4
(902 lL, 5.1 mmol, 1.0 equiv) and Ti(OiPr) (1.5 mL, 5.1 mmol, 1.0 equiv) at rt.
3
4
5
6
.
.
.
.
The mixture was then heated at 60 °C for 24 h (the colorless solution turned into
black-brown and the conversion of the substrate can be followed up by 1H NMR)
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2
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Ò
3
381–3391.
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hydrochloride isolated as amorphous powder with 86–98% yield.
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