Page 7 of 8
Journal Name
Green Chemistry
ARTICLE
[BF4] anion were shown as exceptional media for the selective
synthesis of MAGs (i.e. up to 100% selectivity, without any loss
in the catalytic activity with the reuse). Their SLIL behaviour
facilitates the development of straightforward protocols, based
on cooling and centrifugation steps that allow an easy and full
recovery of both nearly pure MAGs products and the IL and any
other solvent used.
Using this approach, almost pure MAG products were
obtained, while recovery and reuse of the biocatalyst/SLIL
system led to maintenance in activity in agreement with the
demonstrated ability of SLIL to stabilize enzymes. The marriage
between enzymes and the considered Sponge-Like Ionic Liquids
(SLILs) provides synergic opportunities and opens up the way to
8
9
J. Perez-Pariente, I. Díaz, F. Mohino and E. Sastre. Appl. Catal. A:
DOI: 10.1039/C6GC01969B
a) L. Freitas, V. H. Perez, J. C. Santos and H. F. de Castro, J. Braz.
Chem. Soc. 2007, 18, 1360-1366; b) S. Baum, E. Ritter, I. Smirnova,
M. Schilling, and A. Liese, RSC Adv. 2016,
10 a) J. Dupont, R. F. de Souza and P. A. Z. Suarez, Chem. Rev. 2002,
102, 3667-3699; b) J. Dupont and J. D. Scholten, Chem. Soc. Rev
6, 32422-32429.
.
2010, 39, 1780-1804; c) J. P. Hallett and T. Welton, Chem. Rev. 2011,
111, 3508-3576; d) J. Dupont and M. R. Meneghetti, Curr. Opin.
Colloid In. 2013, 18, 54-60, e) A. M. Smith, K. R. J. Lovelock, N. N.
Gosvami, P. Licence, A, Dolan, T. Welton and S. Perkin. J. Phys.
Chem. Lett. 2013, 4, 378-382
new sustainable platforms for developing green chemical 11 a) S. Cantone, U. Hanefeld and A. Basso, Green Chem. 2007,
9
, 954-
processes of industrial interest.
971; b) P. Lozano. Green Chem. 2010, 12, 555-569; c) T. Itoh, J. Synth.
Org. Chem Japan, 2014, 72, 518-528; d) Y. Matsubara, S. Kadotani,
T. Nishihara, Y. Hikino, Y. Fukaya, T. Nokami and T. Itoh,
Biotechnol. J. 2015, 10, 1944-1951; e) P. Lozano, J. M. Bernal S.
Acknowledgements
Nieto, C. Gomez, E. Garcia-Verdugo and S. V. Luis, Chem. Commun
2015, 51, 17361-17374.
.
This work has been partially supported by CTQ-2015-67927-R,
CTQ-2015-68429-R (MINECO/FEDER) and 19278/PI/14
(Fundación SENECA CARM) grants.
12 Wasserscheid P, Welton, T. (Eds) Ionic Liquids in Synthesis, Wiley-
VCH, Weinheim, 2008
13 a) Z. Guo and X. B. Xu, Org. Biomol. Chem. 2005,
Z. Guo and X. B. Xu, Green Chem, 2006, , 54-62; c) Z. Guo, B. Q.
Chen, R. L. Murillo, T. W. Tan and X. B. Xu, Org. Biomol. Chem
2006, , 2772-2776.
3, 2615-2619; b)
Notes and references
Departamento de Bioquímica y Biología Molecular B e Inmunología.
a
8
.
Facultad de Química, Campus Regional de Excelencia Internacional
“Mare Nostrum”. Universidad de Murcia, E-30100 MURCIA. Spain.
4
14 P. Lozano, J. M. Bernal, E. Garcia-Verdugo, G. Sanchez-Gomez, M.
Vaultier, M. I. Burguete, S. V. Luis, Green Chem. 2015, 17, 3706-
3717.
b
Departamento de Química Inorgánica. Facultad de Química, Campus
Regional de Excelencia Internacional “Mare Nostrum”. Universidad de
Murcia, E-30100 MURCIA. Spain.
15 a) P. Lozano, J.M. Bernal, G. Sánchez-Gómez, G. López-López and
c
M. Vaultier. Energy Environ. Sci, 2013, 6, 1328-1338; b) P. Lozano,
Departamento de Química Inorgánica y Orgánica, Universidad Jaume I,
J.M. Bernal and A. Navarro. Green Chem. 2012, 14, 3026-3033; P.
Lozano1, J. M. Bernal, A. Lajarin, D. Romera, E. Garcia-Verdugo, G.
Sanchez-Gomez, M. Pucheault, M. Vaultier, M. I. Burguete and S. V.
Campus del Riu Sec, Avenida Sos Baynant s/n, E-12071, Castellón,
Spain
Electronic Supplementary Information (ESI) available: [details of any
supplementary information available should be included here]. See
DOI: 10.1039/b000000x/
Luis. Curr. Green Chem. 2014, 1, 145-154.
16 a) S. K. Ritter, Chem. Eng. News, 2013, 91, 34–35; b) P Lozano, J. M.
Bernal, C. Gomez, E. García-Verdugo, M. I. Burguete, G. Sánchez, M.
Vaultier and S. V. Luis. Catal. Today, 2015, 255, 54-59.
1
N. J. Zhong, L.Z. Cheong and X. B. Xu. Eur. J, Lipid Sci. Technol.
2014, 116, 97-107.
17 a) J. E. L. Dullius, P. A. Z. Suarez, S. Einloft, R. F. de Souza and J.
Dupont. Organometallics 1998, 17, 815-819; b) P. J. Dyson, D. J. Ellis
and T. Welton, Can. J. Chem. 2001, 79, 705-708.
2
a) H. Zhang, Y. A. Cui, S. M. Zhu, F. Q. Feng and X. D. Zheng. Int
J. Pharm. 2010, 395, 154-160; b) H. Shimada, V. E. Tyler, and J. L.
McLaughlin, J. Nat. Prod. 1997, 60, 417-418.
D. Vollhardt and G. Brezesinski, J. Phys. Chem. C, 2015, 119, 9934-
9946.
18 a) P. Lozano, T. De Diego, D. Carrie, M. Vaultier and J. L. Iborra,
Biotechnol. Lett., 2001, 23, 1529-1533; b) P. Lozano, T. De Diego, S.
Gmouh, M. Vaultier and J. L. Iborra, Biotechnol. Prog. 2003, 19, 380-
382;
3
4
5
6
7
J. I. Garcia, H. Garcia-Marin and E. Pires. Green Chem., 2014, 16
,
19 a) P. Lozano, J. M. Bernal, S. Nieto, C. Gomez, E. Garcia-Verdugo
and S. V. Luis. Chem. Commun. 2015, 51, 17361-17374; b) T. De
Diego, P. Lozano, S. Gmouh, M. Vaultier and J. L. Iborra,
1007-1033.
R. Ciriminna, C. Della Pina, M. Rossi, M. Pagliaro, Eur. J. Lipid Sci.
Technol. 2014, 116, 1432-1439.
Biomacromolecules, 2005, 6, 1457-1464.
M. L. Damstrup, T. Jensen, F. V. Sparso, S.Z. Kiil, A. D. Jensen and
X. Xu. J. Am. Oil Chem. Soc. 2006, 83,27-33.
20 P. Lozano, J. M. Bernal and M. Vaultier. Fuel, 2011. 90, 3461-3467
21 E. Feher, B. Major, K. Belafi-Bako and L. Gubicza. Biochem Soc. T.,
2007, 35, 1624-1627.
European Food Emulsifier Manufactures Association, e.V. E 471, in
EFEMA Index of Food Emulsifiers, June 2015 Ed., pp. 51-56 (see
http://www.emulsifiers.org).
This journal is © The Royal Society of Chemistry 2012
J. Name., 2012, 00, 1‐3 | 7