Tetrahedron Letters p. 7305 - 7306 (1998)
Update date:2022-08-11
Topics:
Moughamir, Khadija
Atmani, Aziz
Mestdagh, Helene
Rolando, Christian
Francesch, Charlette
The nucleophilic fluorination of alkyl iodides, bromides and tosylates and of α-bromo- or α-chloroketones is smoothly effected by tetrabutylammonium hydrogen difluoride in the presence of pyridine, in dioxane or THF, with good or satisfying substitution-to-elimination ratio.
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