Journal of Medicinal Chemistry p. 7166 - 7185 (2017)
Update date:2022-08-15
Topics:
Liu, Jun
Sun, Bin
Zhao, Xiaoyu
Xing, Jie
Gao, Yanhui
Chang, Wenqiang
Ji, Jianbo
Zheng, Hongbo
Cui, Changyi
Ji, Aiguo
Lou, Hongxiang
Protease-activated receptor-1 (PAR1), a G-protein-coupled receptor, plays a critical role in thrombin-mediated platelet aggregation. It is regarded as a promising antithrombosis target that is unlikely to result in bleeding. Here, we describe the synthesi
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