1780
P. Salehi et al.
authentic samples. Monitoring of the reactions was accomplished by
TLC using precoated aluminium sheets, Merck, silica gel 60 F254 (elu-
ent: MeOH/HOAc: 5/1). DABCO-DNODP was prepared according to
the reported procedure,16 and its hydrogen peroxide content was deter-
mined by titration with KMnO4.23 All yields refer to isolated products.
General Procedure for the Oxidation of Thiols
by DABCO-DNODP
DABCO-DNODP (1.6–5.0 mmol) was added to a stirred solution of
thiol (2 mmol) in acetonitrile (7 ml). The mixture was stirred magneti-
cally under reflux condition for the appropriate period of time (Table I).
Progress of the reaction was followed by TLC. The mixture was cooled
and filtered over a sintered glass funnel. Evaporation of the solvent
under reduced pressure followed by preparative thin layer chromatog-
raphy on silica gel afforded the pure products in 45–97% yield.
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