Heterocyclic Communications p. 275 - 280 (2002)
Update date:2022-08-17
Topics:
Charris, Jaime
Monasterios, Melina
Dominguez, Josee
Infante, Wilson
Castro, Norma De
A number of new 5-nitro-2-furfurylidene derivatives 9a-k were synthesized by the reaction of 2-methyl-4-(5-nitro-2-furfurylmethyliden)-Δ2-oxazolin-5-one 6 or 2-phenyl-4-(2-furfurylmethyliden)-Δ2-oxazolin-5-one 7 with appropriate 2-aminobenzothiazole. The compounds synthesized were identified by 1H-NMR, IR, MS and micro analysis. All compounds studied in this work were screened for their in vitro antimicrobial and antifungal activities against the standard strains: Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, and the yeast Candida albicans.
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