Journal of Organic Chemistry p. 3548 - 3553 (1988)
Update date:2022-08-25
Topics:
Radner, Finn
A simple method for the iodination of aromatic compounds, using I- as the iodine source and the O2 and catalytic amounts of NO+BF4- as the oxidant, is presented.The reactions are performed at 25 deg C in CF3COOH/CH2Cl2 or CF3COOH/CH3COOH mixtures and compounds with as different reactivities as the halobenzenes and 1-methoxynaphthalene can be iodinated in very good yields.A set of relative rates, isotope effects, and isomer distributions in accordance with the electrophilic action of an "I+" species are presented.The formation of "I+" is discussed in terms of possible outer-sphere and inner-sphere electron-transfer steps.Aromatic bromination and to a lesser extent chlorination can be performed by using similar methods.
View MoreZHUHAI HAIRUIDE BIOSCIENCE AND TECHNOLOGY CO.,LTD
website:http://www.zhhairuide.com
Contact:+8613326687259/+86-756-7789199
Address:No.10 Yonghui Road
Contact:13357117572
Address:No.149 Shiji dadao Road.
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Contact:86 311 85902108 / 85902109
Address:room 1001-1005 ,huanghe Road ,shijiazhuang ,China
Contact:021-61840961 021-61840962
Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
Doi:10.1039/c7cc01779k
(2017)Doi:10.1016/S0031-9422(00)00101-1
(2000)Doi:10.1080/00397911.2019.1574833
(2019)Doi:10.1039/c1sm05581j
(2011)Doi:10.1021/ol027306q
(2003)Doi:10.1016/j.molstruc.2019.05.013
(2019)