Organic and Biomolecular Chemistry p. 5365 - 5368 (2011)
Update date:2022-08-10
Topics:
Gowda, Maravanhalli Sidde
Pande, Sushanth Sudhir
Ramakrishna, Ramesha Andagar
Prabhu, Kandikere Ramaiah
An efficient user-friendly method of acylation of Grignard reagents to selectively synthesize ketones is presented, which is assisted by simple amides such as NMP, or DMF. The present chemoselective method tolerates a variety of functional groups such as ketone, ester, nitrile and other functional groups.
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