Tetrahedron Letters p. 5269 - 5272 (1998)
Update date:2022-08-10
Topics:
Easton, Christopher J.
Harper, Jason B.
para-Substituted (S)-phenylalanines may be obtained by treatment of the corresponding mixtures of ortho- and para-substituted N-acetyl-(RS)- phenylalanines with Acylase I from porcine kidney. The selectivity of the enzyme may be attributed to its evolution to digest peptide derivatives of (S)-phenylalanine and (S)-tyrosine.
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