Communication
RSC Advances
reaction under the standard conditions independently. No
desired product is detected in each case, suggesting that a free
radical course was involved in the reaction. Minisci and co-
workers showed that decarboxylation of a-oxocarboxylic acids
to give the corresponding carbonyl radicals could be realized at
room temperature in the presence of catalytic amounts of silver
species. We hypothesized that the decarboxylative acylation
might be initiated by carbonyl radicals Scheme 2.
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11
Conclusions
In conclusion, the decarboxylative acylation displays the utility
of this reaction in the functionalization and diversication of
aryl ketone synthesis. We were pleased to nd that the new
catalyst system is effective without modication in our recently
disclosed decarboxylative synthesis of aryl ketones. In this
transformation, a-oxocarboxylates were coupled directly with
arylboronic acids by silver-catalyzed with good function-group
compatibility in aprotic polar solvents.
4
(a) N. Rodr ´ı guez and L. J. Goossen, Chem. Soc. Rev., 2011, 40,
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2
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Acknowledgements
Project supported by the National Natural Science Foundation
of China (no. 21402123 and no. 21172149), the Zhejiang
Provincial Natural Science Foundation of China (no.
LQ14B020001) and the Science Technology Project of Shaoxing
City (no. 2013014017).
9
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RSC Adv., 2014, 4, 48698–48702 | 48701