Heterocycles p. 63 - 66 (1988)
Update date:2022-08-11
Topics:
Tsuda, Yoshisuke
Okuno, Yukihiro
Kanemitsu, Kimihiro
The short step and efficient synthesis of nojirimycin (1) from commercially available 1,2-isopropylidene-D-glucofuranose (2) was described.Oxidation of 2 with (Bu3Sn)2O-Br2 followed by oximation, isomerization, and stereoselective reduction gave the 5-amino derivative of gluco-configuration (6a), which was converted to nojirimycin bisulfite adduct (8) in 50percent overall isolated yield.
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Doi:10.1007/s10953-010-9567-0
(2010)Doi:10.1039/c39910001117
(1991)Doi:10.1007/BF00506891
(1983)Doi:10.1016/j.apcata.2015.02.047
(2015)Doi:10.1021/jacs.7b10377
(2017)Doi:10.1021/jo0484981
(2005)