ORDER
REPRINTS
CHIRAL PEPTIDE NUCLEIC ACID MONOMERS
1397
(CI); 49.025 (CJ); 151.025 (CK); 164.692 (Cl); 110.750 (CM); 12.630 (CN); 141.494
(CO); 23.826 (Pro, γ C); 29.206 (Pro, βC); 46.805 (Pro, δC).
r.t.
Boc-PNA[Trp]-OMe (A). [α]
= 13◦ (1, MeOH). MS, calc. (found):
589 nm
(M+H+) = 527 (527, 428 [- Boc]). 1H NMR: 1.403 (Ha); 5.260 (Hb); 3.557 (Hc);
3.495 (Hd); 4.077 (He); 3.682 (Hf); 4.367 (Hg); 9.277 (Hh); 1.799 (Hi); 6.960
(Hj); 3.013 (Trp, βCH2); 7.036 (indolH5); 7.106 (indH6); 7.165 (indH2); 7.327
(indH7); 7.579 (indH4); 8.798 (indNH); 13C NMR: 28.681 (CA); 78.555 (CB);
155.857 (CC); 48.887 (CD); 51.546 (CE); 49.774 (CF); 169.540 (CG); 52.562 (CH);
167.592 (CI); 48.069 (CJ); 151.387 (CK); 164.289 (Cl); 110.732 (CM); 12.551
(CN); 141.144 (CO); 28.75 (Trp, βCH2); 123.7 (indC5); 119.710 (indC6); 122.241
(indC2); 111.717 (indC7); 118.589 (indC4); 110.460 (indC3); 127.484 (indC8);
136.446 (indC9).
ACKNOWLEDGMENTS
Supported by the Polish State Committee of Scientific Research 3T09A08013
grant.
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