Molecules p. 86 - 97 (2007)
Update date:2022-08-11
Topics:
Gao, Hong
Nishida, Jun
Saito, Shizuka
Kawabata, Jun
Baicalein (1), 6-hydroxyapigenin (6), 6-hydroxygalangin (13) and 6-hydroxykaempferol (14), which are naturally occurring flavonoids from a set of 14 hydroxyflavones tested, exhibited high inhibitory effects on tyrosinase with respect to L-DOPA, while each of the 5,6,7-trihydroxyflavones 1, 6, 13 or 14 acted as a cofactor to monophenolase. Moreover, 6-hydroxykaempferol (14) showed the highest activity and was a competitive inhibitor of tyrosinase compared to L-DOPA. 5,6,7-Trihydroxyflavones 1, 6, 13 or 14 showed also high antioxidant activities. Hence, we conclude that the 5,6,7-trihydroxy-flavones are useful as good depigmentation agents with inhibitory effects in addition to their antioxidant properties.
View MoreChengdu Gelipu Biotechnology Co., Ltd.
website:http://www.glp-china.com
Contact:86-28-82610909
Address:chegndu
Wuxi Pharma-Trading Import & Export Co.,Ltd.
Contact:+86-510-82304590 82716390
Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
Nantong Advance Chemical Co., Ltd
Contact:86-13818730908
Address:Fine Chemical Industry Garden,Beixin Town,Qidong
Chiral Quest (Suzhou) Company Ltd
website:http://www.chiralquest.com
Contact:+86-0512-62956066
Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Contact:+86-10-59484199
Address:No.58-A1026 Liangguan Street
Doi:10.1021/cs501656x
(2015)Doi:10.1080/00397919508011812
(1995)Doi:10.1021/acs.inorgchem.9b03250
(2020)Doi:10.1021/acs.joc.6b03068
(2017)Doi:10.1055/s-0029-1218013
(2009)Doi:10.1021/ja01126a523
(1952)