Organic Letters
Letter
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isolation of the key intermediates involved in the reaction process
added more credence to the proposed mechanism. Finally, the
gram scale reaction using a flow reactor further demonstrated the
synthetically potential applications.
ASSOCIATED CONTENT
* Supporting Information
■
S
The Supporting Information is available free of charge on the
Crystallographic file for 2b (CIF)
Crystallographic file for 9b′ (CIF)
Experimental procedures and 1H and 13C NMR spectra for
AUTHOR INFORMATION
Corresponding Author
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M.; Schmidt, B. M.; Grubert, L.; Patzel, M.; Schwarz, J.; Hecht, S. J. Am.
̈
Notes
Chem. Soc. 2015, 137, 2738. (e) Lvov, A. G.; Shirinian, V. Z.; Zakharov,
A. V.; Krayushkin, M. M.; Kachala, V. V.; Zavarzin, I. V. J. Org. Chem.
2015, 80, 11491.
The authors declare no competing financial interest.
(7) (a) Yu, H.; Li, J.; Kou, Z.; Du, X.; Wei, Y.; Fun, H. K.; Xu, J.; Zhang,
Y. J. Org. Chem. 2010, 75, 2989. (b) Wang, R.; Lu, S. C.; Zhang, Y. M.;
Shi, Z. J.; Zhang, W. Org. Biomol. Chem. 2011, 9, 5802.
(8) Zheng, L. W.; Yang, C.; Xu, Z.; Gao, F.; Xia, W. J. J. Org. Chem.
2015, 80, 5730.
ACKNOWLEDGMENTS
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We are grateful for support from China NSFC (Nos. 21272047,
21372055, and 21472030), SKLUWRE (No. 2015DX01), the
Fundamental Research Funds for the Central Universities
(Grant No. HIT.BRETIV.201310), and HLJNSF (B201406).
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