of the complex of 3a and OYE1 was used to build a model of the
corresponding complex with NCR.
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10 For the stereoselective bioreduction of a-methylcinnamaldehyde (3a)
see: A. Mu¨ller, B. Hauer and B. Rosche, Biotechnol. Bioeng., 2007, 98,
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11 (a) M. Hall, C. Stueckler, W. Kroutil, P. Macheroux and K. Faber,
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The authors would like to express their cordial thanks for financial
support by BASF SE and to R. Stu¨rmer, B. Hauer and K. Ditrich
for stimulating discussions, and to W. Hoeffken (Ludwigshafen)
for providing the coordinates of NCR. N. C. Bruce and H.
Housden (York) are thanked for the generous donation of PETN-,
NEM- and morphinone reductase.
12 A. Scrivanti, M. Bertoldini, V. Beghetto and U. Matteoli, Tetrahedron,
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