10.1002/chem.202002860
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Melting curves were plotted in GraphPad Prism V6.0 and interpolated to
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Acknowledgements Text. AK and TC acknowledge funding from
the Marie Skłodowska-Curie Innovative Training Network (ITN)
ClickGene
(H2020-MSCA-ITN-2014-642023).
AK
also
acknowledges funding from Science Foundation Ireland Career
Development Award (SFI-CDA) [15/CDA/3648] and from CÚRAM
[17/RC-PhD/3480]. Mass spectrometry and UV analysis was
carried out at the Nano Research Facility in Dublin City University
which was funded under the Programme for Research in Third
Level Institutions (PRTLI) Cycle 5. The PRTLI is co-funded
through the European Regional Development Fund (ERDF), part
of the European Union Structural Funds Programme 2011-2015.
TC acknowledges funding from the German Research
Foundation (DFG) through SFB1032. We are grateful to the
Carlsberg Foundation (grant CF15-0675) for funding towards the
X-ray diffractometer. CS acknowledges funding from Science
Foundation Ireland Technology Innovation Development Award
(18/TIDA/6111). The authors would like to thank Prof. Tom Brown
(University of Oxford) and ATDBio Ltd. (Southampton, UK) for
donating BCN.
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Keywords: Chemical nuclease • DNA triplexes • Click chemistry
• Copper • DNA damage
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