Bioorganic and Medicinal Chemistry Letters p. 267 - 269 (2005)
Update date:2022-08-29
Topics:
Cheng, Jun
Xie, Jiangtao
Luo, Xianjin
Some benzimidazole derivatives were synthesized and the antiviral evaluation against Coxsackie virus B3 is reported. These compounds are proved to be excellent inhibitors of CVB3. Some benzimidazole derivatives were synthesized and evaluated for their antiviral properties. Compounds 20 and 21 showed potent selective activity against Coxsackie virus B3 in VERO cells. Some structure-activity relationships were discussed.
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