Synthetic Communications p. 1286 - 1290 (2014)
Update date:2022-08-29
Topics:
Liu, Di
Zhou, Shixue
Gao, Jun
An efficient one-pot synthesis of hydroxylnaphthalene-1,4-dione derivatives is accomplished by a three-component reaction of 2-hydroxynaphthalene-1,4- dione, aromatic aldehydes, and amines in water under ambient temperature catalyzed by phenylphosphinic acid. This method has the advantages of good yield, mild reaction conditions, simple workup, environmental friendliness and cost efficiency.
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