L. Wang et al.
Acknowledgment
This work was supported by Fund of Natural Science Foundation of
Heilongjiang Province of China (no. B201208).
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Conclusions
We have developed a palladium-catalyzed direct C–H cyanation of
picolinamides via bidentate chelation assistance. The present
approach is convenient with easy operation, uses an inexpensive
catalytic system and has broad substrate scope. In addition, the
cyanated product could transform into valuable compounds in
good yields. A plausible mechanism is proposed to account for
the formation of products. Further experiments are currently under-
way in our laboratory.
Supporting Information
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Appl. Organometal. Chem. (2016)