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Z. Cai et al.
Letter
Synlett
Acknowledgment
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Leifert, D.; Studer, A. Org. Lett. 2013, 15, 928. (c) Seo, S.; Slater,
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This work was supported financially by the Scientific Research Foun-
dation of the Education Department of Liaoning Province (L2015383)
and the Doctoral Start-Up Fund of Shenyang University of Technology
(No. 521422).
Supporting Information
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Supporting information for this article is available online at
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ortiInfogrmoaitn
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3-Bromo-9H-fluoren-9-one (3j)
1
Yield: 59%. H NMR (500 MHz, CDCl3): δ = 7.66 (d, J = 8.2 Hz, 1
H), 7.57 (d, J = 8.2 Hz, 1 H), 7.52–7.47 (m, 3 H), 7.35–7.31 (m, 1
H), 7.25 (t, J = 6.4 Hz, 1 H). 13C NMR (125 MHz, CDCl3): δ = 192.3,
146.1, 143.1, 140.9, 134.8, 134.3, 132.3, 129.8, 128.9, 125.3,
124.5, 120.9, 120.5. HRMS: m/z calcd for C13H7BrO: 259.0981;
found: 259.0980
3-Fluoro-6-methoxy-9H-fluoren-9-one (3n)
Yield: 62%. 1H NMR (500 MHz, CDCl3): δ = 7.53–7.49 (m, 1 H),
7.42 (d, J = 8.2 Hz, 1 H), 7.16 (s, 1 H), 7.02 (m, 2 H), 6.83 (m, 1 H),
3.76 (s, 3 H). 13C NMR (125 MHz, CDCl3): δ = 191.7, 167.2 (d,
J = 254 Hz), 147.3 (d, J = 10.2 Hz), 145.8, 143.2 (d, J = 2.4 Hz),
132.3, 130.3, 126.2 (d, J = 10.2 Hz), 124.2, 121.4, 115.3 (d,
J = 22.8 Hz), 108.2 (d, J = 24.4 Hz), 56.5. HRMS: m/z calcd for
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H.; Guram, A. S. J. Org. Chem. 2004, 69, 8626.
C
14H9FO2: 228.2185; found: 228.2189.
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© Georg Thieme Verlag Stuttgart · New York — Synlett 2016, 27, 395–398