Synthetic Communications p. 1507 - 1518 (2016)
Update date:2022-08-11
Topics:
Zhang, Zeyuan
Xie, Caixia
Feng, Lei
Ma, Chen
An efficient p-toluene sulfonic acid–catalyzed, one-pot, two-step oxidative system for cyclization of o-diaminobenzene with 1,2-diaryl-2-hydroxyethanone to quinoxalines was described. A nontoxic, readily available oxidant, dimethylsulfoxide (DMSO), was applied in this process. A broad range of substrates was applied to this method, and target compounds were obtained with good yields.
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