B. Maleki et al. / Chinese Chemical Letters 21 (2010) 1346–1349
1349
1.1. General procedure for the synthesis of 2,4,6-triarylpyridines
To a stirred mixture of the aldehydes 1 (1 mmol), ketones 2 (2 mmol) and ammonium acetate (1.3 mmol) at room
temperature were added TCT (5 mol%) and H2O (2 drops) and then temperature was raised to 130 8C and maintained
for the appropriate time (Table 2). After the completion of the reaction (as monitored by TLC), the reaction mixture
was diluted with EtOH (96%, 5 mL) and stirred for 2 min at 130 8C. The solvent was evaporated; the remaining solid
products were collected and washed with water to give the crude products. Then, recrystallization from EtOH (96%,
5 mL) provided pure 2,4,6-triarylpyridines.
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