Chemistry of Heterocyclic Compounds p. 234 - 237 (1994)
Update date:2022-08-11
Topics:
Usol'tseva, S. V.
Andronnikova, G. P.
In the interaction of 2-α-chlorobenzylidenehydrazino-4-ethoxycarbonylthiazole with nucleophiles, two competing reactions take place: 1) nucleophilic replacement of the chlorine atom to form the corresponding substitution product; 2) elimination of a hydrogen chloride molecule, concluding in cyclization of the intermediate nitrilimine to form 3-phenyl-5-ethoxycarbonylthiazolo<2,3-c>-1,2,4-triazole.The direction taken by the interaction depends on the nature of the nucleophile and is determined primarily by the ratio of basicity and nucleophilicity of the agent.
View MoreContact:86-791-86629460
Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
RongCheng Tianyu Technology Co.,Ltd.
Contact:86-631-7519595
Address:220Ping Donghai Road RongChengCity,ShangDong Province China
website:http://www.easchem.com
Contact:+86-731-89722861 89722891
Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
Contact:+86-511-88790000
Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016
He Bei Shun Er Chemical Co., LTD.
Contact:86-0311-86996932/86860168
Address:No 18,North street
Doi:10.1016/S0022-328X(00)83729-8
(1967)Doi:10.1002/chem.201302550
(2013)Doi:10.1007/s11164-016-2786-2
(2017)Doi:10.1016/j.tetlet.2021.153183
(2021)Doi:10.1039/b105567b
(2001)Doi:10.1080/15257770.2020.1832694
(2020)