Journal of the American Chemical Society p. 5162 - 5166 (1994)
Update date:2022-08-10
Topics:
Tanko, James M.
Suleman, N. Kamrudin
The results reported herein demonstrate that the chemoselectivity (SH2 ring opening vs abstraction of a cyclopropyl hydrogen) associated with the free radical chlorination of cyclopropane is solvent dependent. Internal pressure is implicated as the solvent parameter responsible for the observed solvent effect. (Solvents of high internal pressure favor the SH2 process; hydrogen abstraction becomes more important in solvents of low internal pressure or in the gas phase.) Extrapolation of the solution phase results to zero internal pressure accurately predicts the gas-phase result, suggesting that the difference in chemoselectivity between the vapor- and condensed-phase reactions is attributable to internal pressure in the condensed phase medium. No evidence for the chlorine atom cage effect is found in the chlorination of cyclopropane.
View MoreShanghai Synmedia Chemical Co., Ltd
Contact:+86-21-38681880
Address:6th Floor, 11A Building, No.528 Ruiqing Road, Heqing town, Pudong new district, Shanghai China
Xi'an Tizan Tech & Industry Co., Ltd.
Contact:86-18629066522
Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.
shanghai Tauto Biotech Co., Ltd
website:http://www.tautobiotech.com/en/index.htm
Contact:+86-21-51320588 ext. 8025
Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Wuhan Jadechem International Trade Co.,Ltd.
website:http://www.jadechem-intl.com
Contact:+86-27-83527060
Address:Room502,Building C11,Software new city No.9,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China
Suzhou Health Chemicals Co., Ltd.
website:http://www.healthchems.com
Contact:13776257979
Address:No. 338, Jingang Avenue,
Doi:10.1081/SCC-100105394
(2001)Doi:10.1016/j.molstruc.2020.129360
(2021)Doi:10.1016/S0040-4020(01)93278-8
(1981)Doi:10.1002/jccs.201700082
(2017)Doi:10.1016/S0960-894X(03)00498-0
(2003)Doi:10.1016/S0026-0495(00)80040-2
(1957)